I can think of a few to add to the list:
- replace George Michael with Freddie Mercury
- swap Jack Spyerek (The Trews) with Gary Low (ex-Big Sugar)
- let old-school, talented Michael Jackson take over from the alien who is currently in possession of his body
- substitute Tom Waits for Diana Krall (just for a little while)
- have Holly Cole cover for Tori Amos
- give Harry Connick Jr. the day off while Big Rude Jake fills in
- better yet, Big Rude Jake for Johnny Favourite
- MC 900 Ft. Jesus for Beck
- anyone, ANYONE for Jessica Simpson. I've heard coat racks with more talent than she has.
- let's replace Michael Stipe (R.E.M.) (who's voice is like nails on a chalkboard) with Gord Downie (The Tragically Hip), and Colin MacDonald (The Trews) can sub in for him.
- Shane McGowan (The Pogues) for Leonard Cohen
- Jimi Hendrix for Eric Clapton - hell, Joe Perry (Aerosmith) for Eric Clapton!
- Janis Joplin can cover for Courntey Love
- wouldn't it be interesting to see what Bjork could do with Celine Dion's music?